Monocyte expressed macromolecular C1 and C1q receptors as molecular sensors of danger: Implications in SLE.

The ability of circulating blood monocytes to express C1q receptors (cC1qR and gC1qR)synthesize and secrete the classical pathway proteins C1q, C1r and C1s and their regulator, C1-INH is very well established. What is intriguing however is that, in addition to secretion of the individual proteins mo...

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Bibliographic Details
Main Authors: Berhane eGhebrehiwet, Kinga K Hosszu, Alisa M Valentino, Yan eJi, Ellinor I.B. Peerschke
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
c1q
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00278/full