Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

Abstract Background Major challenges in understanding the functional consequences of genetic risk factors for human disease are which tissues and cell types are affected and the limited availability of suitable tissue. The aim of this study was to evaluate tissue-specific genotype-epigenetic charact...

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Bibliographic Details
Main Authors: Sally Mortlock, Restuadi Restuadi, Rupert Levien, Jane E. Girling, Sarah J. Holdsworth-Carson, Martin Healey, Zhihong Zhu, Ting Qi, Yang Wu, Samuel W. Lukowski, Peter A. W. Rogers, Jian Yang, Allan F. McRae, Jenny N. Fung, Grant W. Montgomery
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
DNA methylation quantitative trait loci (mQTL)
Endometrium
Blood
Menstrual cycle
Endometriosis
Online Access:http://link.springer.com/article/10.1186/s13148-019-0648-7

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http://link.springer.com/article/10.1186/s13148-019-0648-7

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