Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

Clinical management of abdominal aortic aneurysm (AAA) is currently limited to elective surgical repair because an effective pharmacotherapy is still awaited. Inhibition of histone deacetylase (HDAC) activity could be a promising therapeutic option in cardiovascular diseases. We aimed to characteris...

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Bibliographic Details
Main Authors: María Galán, Saray Varona, Mar Orriols, José Antonio Rodríguez, Silvia Aguiló, Jaume Dilmé, Mercedes Camacho, José Martínez-González, Cristina Rodriguez
Format: Article
Language:English
Published: The Company of Biologists 2016-05-01
Series:Disease Models & Mechanisms
Subjects:
Abdominal aortic aneurysm
Histone deacetylases
Inflammation
Vascular remodelling
Metalloproteinases
Online Access:http://dmm.biologists.org/content/9/5/541

Internet

http://dmm.biologists.org/content/9/5/541

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