Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.

Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.

<h4>Background</h4>In Phase II/III randomized controlled clinical trials for the treatment of acute uncomplicated malaria, pyronaridine-artesunate demonstrated high efficacy and a safety profile consistent with that of comparators, except that asymptomatic, mainly mild-to-moderate transi...

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Main Authors: Gaston Tona Lutete, Ghyslain Mombo-Ngoma, Serge-Brice Assi, Jude D Bigoga, Felix Koukouikila-Koussounda, Nsengi Y Ntamabyaliro, Francine Ntoumi, Selidji T Agnandji, Mirjam Groger, Jangsik Shin, Isabelle Borghini-Fuhrer, Sarah Arbe-Barnes, Stephen J Allen, Peter G Kremsner, Robert Miller, Stephan Duparc, Michael Ramharter, CANTAM study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003669

Internet

https://doi.org/10.1371/journal.pmed.1003669

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