Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains
Food-grade titanium dioxide (TiO<sub>2</sub>) containing a nanoparticle fraction (TiO<sub>2</sub> NPs -nanoparticles) is widely used as a food additive (E171 in the EU). In recent years, it has increasingly been raising controversies as to the presence or absence of its harmf...
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doaj-60c1576548aa4ef1a003fd19f9a433302021-04-25T23:02:09ZengMDPI AGFoods2304-81582021-04-011093993910.3390/foods10050939Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria StrainsEwa Baranowska-Wójcik0Klaudia Gustaw1Dominik Szwajgier2Patryk Oleszczuk3Bożena Pawlikowska-Pawlęga4Jarosław Pawelec5Justyna Kapral-Piotrowska6Department of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences, Skromna Street 8, 20-704 Lublin, PolandDepartment of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences, Skromna Street 8, 20-704 Lublin, PolandDepartment of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences, Skromna Street 8, 20-704 Lublin, PolandDepartment of Radiochemistry and Environmental Chemistry, Faculty of Chemistry, Maria Curie-Skłodowska University, 20-031 Lublin, PolandDepartment of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, PolandInstitute Microscopic Laboratory, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, PolandDepartment of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, PolandFood-grade titanium dioxide (TiO<sub>2</sub>) containing a nanoparticle fraction (TiO<sub>2</sub> NPs -nanoparticles) is widely used as a food additive (E171 in the EU). In recent years, it has increasingly been raising controversies as to the presence or absence of its harmful effects on the gastrointestinal microbiota. The complexity and variability of microbiota species present in the human gastrointestinal tract impede the assessment of the impact of food additives on this ecosystem. As unicellular organisms, bacteria are a very convenient research model for investigation of the toxicity of nanoparticles. We examined the effect of TiO<sub>2</sub> (three types of food-grade E171 and one TiO<sub>2</sub> NPs, 21 nm) on the growth of 17 strains of lactic acid bacteria colonizing the human digestive tract. Each bacterial strain was treated with TiO<sub>2</sub> at four concentrations (60, 150, 300, and 600 mg/L TiO<sub>2</sub>). The differences in the growth of the individual strains were caused by the type and concentration of TiO<sub>2</sub>. It was shown that the growth of a majority of the analyzed strains was decreased by the application of E171 and TiO<sub>2</sub> NPs already at the concentration of 150 and 300 mg/L. At the highest dose (600 mg/L) of the nanoparticles, the reactions of the bacteria to the different TiO<sub>2</sub> types used in the experiment varied.https://www.mdpi.com/2304-8158/10/5/939TiO<sub>2</sub> NPsnanoparticlesE171bacterialmicrobiome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ewa Baranowska-Wójcik Klaudia Gustaw Dominik Szwajgier Patryk Oleszczuk Bożena Pawlikowska-Pawlęga Jarosław Pawelec Justyna Kapral-Piotrowska |
spellingShingle |
Ewa Baranowska-Wójcik Klaudia Gustaw Dominik Szwajgier Patryk Oleszczuk Bożena Pawlikowska-Pawlęga Jarosław Pawelec Justyna Kapral-Piotrowska Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains Foods TiO<sub>2</sub> NPs nanoparticles E171 bacterial microbiome |
author_facet |
Ewa Baranowska-Wójcik Klaudia Gustaw Dominik Szwajgier Patryk Oleszczuk Bożena Pawlikowska-Pawlęga Jarosław Pawelec Justyna Kapral-Piotrowska |
author_sort |
Ewa Baranowska-Wójcik |
title |
Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains |
title_short |
Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains |
title_full |
Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains |
title_fullStr |
Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains |
title_full_unstemmed |
Four Types of TiO<sub>2</sub> Reduced the Growth of Selected Lactic Acid Bacteria Strains |
title_sort |
four types of tio<sub>2</sub> reduced the growth of selected lactic acid bacteria strains |
publisher |
MDPI AG |
series |
Foods |
issn |
2304-8158 |
publishDate |
2021-04-01 |
description |
Food-grade titanium dioxide (TiO<sub>2</sub>) containing a nanoparticle fraction (TiO<sub>2</sub> NPs -nanoparticles) is widely used as a food additive (E171 in the EU). In recent years, it has increasingly been raising controversies as to the presence or absence of its harmful effects on the gastrointestinal microbiota. The complexity and variability of microbiota species present in the human gastrointestinal tract impede the assessment of the impact of food additives on this ecosystem. As unicellular organisms, bacteria are a very convenient research model for investigation of the toxicity of nanoparticles. We examined the effect of TiO<sub>2</sub> (three types of food-grade E171 and one TiO<sub>2</sub> NPs, 21 nm) on the growth of 17 strains of lactic acid bacteria colonizing the human digestive tract. Each bacterial strain was treated with TiO<sub>2</sub> at four concentrations (60, 150, 300, and 600 mg/L TiO<sub>2</sub>). The differences in the growth of the individual strains were caused by the type and concentration of TiO<sub>2</sub>. It was shown that the growth of a majority of the analyzed strains was decreased by the application of E171 and TiO<sub>2</sub> NPs already at the concentration of 150 and 300 mg/L. At the highest dose (600 mg/L) of the nanoparticles, the reactions of the bacteria to the different TiO<sub>2</sub> types used in the experiment varied. |
topic |
TiO<sub>2</sub> NPs nanoparticles E171 bacterial microbiome |
url |
https://www.mdpi.com/2304-8158/10/5/939 |
work_keys_str_mv |
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