Modeling initiation of Ewing sarcoma in human neural crest cells.

Modeling initiation of Ewing sarcoma in human neural crest cells.

Ewing sarcoma family tumors (ESFT) are aggressive bone and soft tissue tumors that express EWS-ETS fusion genes as driver mutations. Although the histogenesis of ESFT is controversial, mesenchymal (MSC) and/or neural crest (NCSC) stem cells have been implicated as cells of origin. For the current st...

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Bibliographic Details
Main Authors: Cornelia von Levetzow, Xiaohua Jiang, Ynnez Gwye, Gregor von Levetzow, Long Hung, Aaron Cooper, Jessie Hao-Ru Hsu, Elizabeth R Lawlor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084816?pdf=render

Internet

http://europepmc.org/articles/PMC3084816?pdf=render

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