Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation

Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation

Inefficient removal of dying retinal pigment epithelial (RPE) cells by professional phagocytes can result in debris formation and development of age-related macular degeneration (AMD). Chronic oxidative stress and inflammation play an important role in AMD pathogenesis. Only a few well-established i...

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Bibliographic Details
Main Authors: Mária Szatmári-Tóth, Tanja Ilmarinen, Alexandra Mikhailova, Heli Skottman, Anu Kauppinen, Kai Kaarniranta, Endre Kristóf, Lyubomyr Lytvynchuk, Zoltán Veréb, László Fésüs, Goran Petrovski
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
age-related macular degeneration
anoikis
autophagy
hESC-RPE
inflammation
macrophages
phagocytosis
triamcinolone
Online Access:https://www.mdpi.com/1422-0067/20/4/926

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https://www.mdpi.com/1422-0067/20/4/926

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