Development of AR-V7 as a putative treatment selection marker for metastatic castration-resistant prostate cancer

Development of AR-V7 as a putative treatment selection marker for metastatic castration-resistant prostate cancer

Prostate cancer cells demonstrate a remarkable "addiction" to androgen receptor (AR) signaling in all stages of disease progression. As such, suppression of AR signaling remains the therapeutic goal in systemic treatment of prostate cancer. A number of molecular alterations arise in patien...

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Bibliographic Details
Main Author: Jun Luo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Asian Journal of Andrology
Subjects:
androgen receptor; androgen receptor splice variant-7 (AR-V7); castration-resistance prostate cancer; circulating tumor cells; treatment selection
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=4;spage=580;epage=585;aulast=Luo

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=4;spage=580;epage=585;aulast=Luo

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