A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

The exocytosis of synaptic vesicles (SVs) elicited by potent stimulation is rapidly compensated by bulk endocytosis of SV membranes leading to large endocytic vacuoles (‘bulk’ endosomes). Subsequently, these vacuoles disappear in parallel with the reappearance of new SVs. We have used synapses of dy...

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Bibliographic Details
Main Authors: Yumei Wu, Eileen T O'Toole, Martine Girard, Brigitte Ritter, Mirko Messa, Xinran Liu, Peter S McPherson, Shawn M Ferguson, Pietro De Camilli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
high pressure freezing
syndapin
endosome
exocytosis
synaptic transmission
Online Access:https://elifesciences.org/articles/01621

Internet

https://elifesciences.org/articles/01621

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