Sample size and power determination when limited preliminary information is available

Sample size and power determination when limited preliminary information is available

Abstract Background We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI), an experimenta...

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Bibliographic Details
Main Authors: Christine E. McLaren, Wen-Pin Chen, Thomas D. O’Sullivan, Daniel L. Gillen, Min-Ying Su, Jeon H. Chen, Bruce J. Tromberg
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Medical Research Methodology
Subjects:
Power and sample size calculation
Tamoxifen
Breast density
Magnetic resonance imaging
Diffuse optical spectroscopic imaging
Online Access:http://link.springer.com/article/10.1186/s12874-017-0329-1

Internet

http://link.springer.com/article/10.1186/s12874-017-0329-1

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