Sample size and power determination when limited preliminary information is available
Abstract Background We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI), an experimenta...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-04-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12874-017-0329-1 |