Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation.

BACKGROUND: Histamine drives pruritus in allergic skin diseases which clinically constitutes a most disruptive symptom. Skin pathology in allergic skin diseases is crucially influenced by different T-helper subsets. However, the contribution of different histamine-receptors to T-helper cell dependen...

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Bibliographic Details
Main Authors: Subhashree Mahapatra, Melanie Albrecht, Barbara Behrens, Adan Jirmo, Georg Behrens, Christina Hartwig, Detlef Neumann, Ulrike Raap, Heike Bähre, Christina Herrick, Anna-Maria Dittrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913588?pdf=render