The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury

The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury

Traumatic brain injury (TBI) represents an important problem of global health. The damage related to TBI is first due to the direct injury and then to a secondary phase in which neuroinflammation plays a key role. NLRP3 inflammasome is a component of the innate immune response and different diseases...

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Bibliographic Details
Main Authors: Natasha Irrera, Massimo Russo, Giovanni Pallio, Alessandra Bitto, Federica Mannino, Letteria Minutoli, Domenica Altavilla, Francesco Squadrito
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
traumatic brain injury
NLRP3 inflammasome
neuroinflammation
pyroptosis
SARS-CoV-2
Online Access:https://www.mdpi.com/1422-0067/21/17/6204

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