The Clinical and Pathological Profile of BRCA1 Gene Methylated Breast Cancer Women: A Meta-Analysis

The Clinical and Pathological Profile of BRCA1 Gene Methylated Breast Cancer Women: A Meta-Analysis

Background: DNA aberrant hypermethylation is the major cause of transcriptional silencing of the breast cancer gene 1 (BRCA1) gene in sporadic breast cancer patients. The aim of the present meta-analysis was to analyze all available studies reporting clinical characteristics of BRCA1 gene hypermethy...

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Bibliographic Details
Main Authors: Ilary Ruscito, Maria Luisa Gasparri, Maria Paola De Marco, Flavia Costanzi, Aris Raad Besharat, Andrea Papadia, Thorsten Kuehn, Oreste Davide Gentilini, Filippo Bellati, Donatella Caserta
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
BRCA1
methylation
breast cancer
epigenetics
tumor progression
DNA
Online Access:https://www.mdpi.com/2072-6694/13/6/1391

Internet

https://www.mdpi.com/2072-6694/13/6/1391

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