The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition

Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the present study was to investigate the mRNA exp...

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Bibliographic Details
Main Authors: Soufi Farhad Ghadiri, Zonouzi Ali Akbar Poursadegh, Eftekhar Ebrahim, Kamali Kamila, Chegeni Sara Aghakhani, Zonouzi Ahmad Poursadegh
Format: Article
Language:English
Published: Sciendo 2018-07-01
Series:Endocrine Regulations
Subjects:
Online Access:https://doi.org/10.2478/enr-2018-0014