The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the present study was to investigate the mRNA exp...
Main Authors: | Soufi Farhad Ghadiri, Zonouzi Ali Akbar Poursadegh, Eftekhar Ebrahim, Kamali Kamila, Chegeni Sara Aghakhani, Zonouzi Ahmad Poursadegh |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2018-07-01
|
Series: | Endocrine Regulations |
Subjects: | |
Online Access: | https://doi.org/10.2478/enr-2018-0014 |
Similar Items
-
Expression levels of the microRNA maturing microprocessor complex components; Drosha, Dicer, and DGCR8 in PBMCs from ankylosing spondylitis patients
by: Zeinab Tabrizi, et al.
Published: (2017-01-01) -
ارزیابی میزان آنزیمهای Drosha، Dicer و پروتئین DGCR8 در بیماران مبتلا به پرهاکلامپسی
by: رقیه درگاهی, et al.
Published: (2018-02-01) -
Diagnostic and Prognostic Potential of MicroRNA Maturation Regulators Drosha, AGO1 and AGO2 in Urothelial Carcinomas of the Bladder
by: Anja Rabien, et al.
Published: (2018-05-01) -
DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex
by: Nadin Hoffmann, et al.
Published: (2018-04-01) -
MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer
by: Timothy M. Johanson, et al.
Published: (2013-01-01)