Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population

Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population

Introduction: Twenty-five – fifty percent of skin melanomas arise from nevi. Melanocyte proliferation is activated by BRAF V600E , then is arrested, but single nevi transform to melanomas. p16 controls arrest, and p16 loss may promote transformation. Aim : To analyze BRAF V600E , p16 express...

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Bibliographic Details
Main Authors: Małgorzata Mackiewicz-Wysocka, Patrycja Czerwińska, Violetta Filas, Elżbieta Bogajewska, Agata Kubicka, Anna Przybyła, Ewelina Dondajewska, Tomasz Kolenda, Andrzej Marszałek, Andrzej Mackiewicz
Format: Article
Language:English
Published: Termedia Publishing House 2017-10-01
Series:Advances in Dermatology and Allergology
Subjects:
melanoma
nevi
BRAF
CDKN2A
p16
Ki67
Online Access:https://www.termedia.pl/Oncogenic-BRAF-mutations-and-p16-expression-in-melanocytic-nevi-and-melanoma-in-the-Polish-population,7,30911,1,1.html

Internet

https://www.termedia.pl/Oncogenic-BRAF-mutations-and-p16-expression-in-melanocytic-nevi-and-melanoma-in-the-Polish-population,7,30911,1,1.html

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