Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population
Introduction: Twenty-five – fifty percent of skin melanomas arise from nevi. Melanocyte proliferation is activated by BRAF V600E , then is arrested, but single nevi transform to melanomas. p16 controls arrest, and p16 loss may promote transformation. Aim : To analyze BRAF V600E , p16 express...
Main Authors: | Małgorzata Mackiewicz-Wysocka, Patrycja Czerwińska, Violetta Filas, Elżbieta Bogajewska, Agata Kubicka, Anna Przybyła, Ewelina Dondajewska, Tomasz Kolenda, Andrzej Marszałek, Andrzej Mackiewicz |
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Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2017-10-01
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Series: | Advances in Dermatology and Allergology |
Subjects: | |
Online Access: | https://www.termedia.pl/Oncogenic-BRAF-mutations-and-p16-expression-in-melanocytic-nevi-and-melanoma-in-the-Polish-population,7,30911,1,1.html |
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