Gene prioritization for imaging genetics studies using Gene Ontology and a stratified False Discovery Rate approach

Gene prioritization for imaging genetics studies using Gene Ontology and a stratified False Discovery Rate approach

Imaging genetics is an emerging field in which the association between genes and neuroimaging-based quantitative phenotypes are used to explore the functional role of genes in neuroanatomy and neurophysiology in the context of healthy function and neuropsychiatric disorders. The main obstacle for re...

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Bibliographic Details
Main Authors: Sejal ePatel, Min Tae Matt Park, Mallar eChakravarty, Jo eKnight
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Neuroinformatics
Subjects:
imaging genetics
genome wide association study
Alzheimer’s disease (AD)
magnetic resonance imaging (MRI)
stratified false discovery rate
Gene Ontology network
Online Access:http://journal.frontiersin.org/Journal/10.3389/fninf.2016.00014/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fninf.2016.00014/full

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