Clostridium difficile Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization

Clostridium difficile Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization

Clostridium difficile has become the most common single cause of hospital-acquired infection over the last decade in the United States. Colonization resistance to the nosocomial pathogen is primarily provided by the gut microbiota, which is also involved in clearing the infection as the community re...

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Bibliographic Details
Main Authors: Matthew L. Jenior, Jhansi L. Leslie, Vincent B. Young, Patrick D. Schloss
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSphere
Subjects:
16S rRNA gene sequencing
Clostridium difficile
colonization resistance
machine learning
microbiome
systems biology
metabolomics
metagenomics
metatranscriptomics
microbial ecology
Online Access:https://doi.org/10.1128/mSphere.00261-18

Internet

https://doi.org/10.1128/mSphere.00261-18

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