Mediators Involved in Decreasing Peripheral Vascular Resistance With Carbachol in the Rat Hind Limb Perfusion Model

We examined the involvement of nitric oxide (NO) and/or endothelium-derived hyperpolarizing factor (EDHF) in decreasing peripheral vascular resistance in the rat hind limb perfusion model and analyzed the identity of EDHF in this model. The potency of carbachol (CCh) to produce relaxation was quanti...

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Bibliographic Details
Main Authors: Renzo Y. Loyaga-Rendon, Shuichi Sakamoto, Takeshi Aso, Keiko Iwasaki-Kurashige, Ryoko Takahashi, Hiroshi Azuma
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319321796