Endocytic protein intersectin1-S shuttles into nucleus to suppress the DNA replication in breast cancer

Abstract Breast cancer is the most common type of cancer worldwide. However, the well-known molecular biomarkers are not enough to meet the needs of precision medicine. In search for novel targets in this regard, we reported ITSN1 (intersectin1) as one of the candidates through mRNA microarray analy...

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Bibliographic Details
Main Authors: Huikun Zhang, Zhifang Guo, Xiaoli Liu, Yawen Zhao, Yongzi Chen, Ming Zhang, Li Fu, Feng Gu, Yongjie Ma
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04218-1