Inhibitory role of Notch1 in calcific aortic valve disease.

Inhibitory role of Notch1 in calcific aortic valve disease.

Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification in families with inherited disease. The Notch signaling...

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Bibliographic Details
Main Authors: Asha Acharya, Chetan P Hans, Sara N Koenig, Haley A Nichols, Cristi L Galindo, Harold R Garner, Walter H Merrill, Robert B Hinton, Vidu Garg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3218038?pdf=render

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http://europepmc.org/articles/PMC3218038?pdf=render

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