Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice

Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice

Background: The increasing incidence and prevalence of atopic dermatitis (AD) demands new therapeutic approaches for treating the disease. We investigated the therapeutic efficacy of immunomodulator FTY720 ointment (fingolimod) for mite-induced intractable AD using an NC/Nga mouse model. Methods: Fe...

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Bibliographic Details
Main Authors: Takumi Tsuji, Satoshi Okuno, Ayano Kuroda, Junya Hamazaki, Takuma Chikami, Sakura Sakurai, Yuya Yoshida, Rie Banno, Tetsuro Fujita, Takeyuki Kohno
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Allergology International
Subjects:
Atopic dermatitis
Epidermal barrier function
Filaggrin
FTY720 ointment
NC/Nga mice
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015002051

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http://www.sciencedirect.com/science/article/pii/S1323893015002051

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