Emerging players in the initiation of eukaryotic DNA replication

<p>Abstract</p> <p>Faithful duplication of the genome in eukaryotes requires ordered assembly of a multi-protein complex called the pre-replicative complex (pre-RC) prior to S phase; transition to the pre-initiation complex (pre-IC) at the beginning of DNA replication; coordinated...

Full description

Bibliographic Details
Main Authors: Shen Zhen, Prasanth Supriya G
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Cell Division
Subjects:
ORC
MCM
RPC
Online Access:http://www.celldiv.com/content/7/1/22