Microarchitecture of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva: An HR-pQCT Case Series

Microarchitecture of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva: An HR-pQCT Case Series

It is challenging to study heterotopic ossification (HO) in patients with fibrodysplasia ossificans progressiva (FOP) due to the contraindication of invasive techniques (i.e., bone biopsies), which can trigger flare-ups. The aim of this case study was to assess mature HO at the microarchitectural le...

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Bibliographic Details
Main Authors: Esmée Botman, Melissa S. A. M. Bevers, Caroline E. Wyers, Bert van Rietbergen, Bernd P. Teunissen, Pieter G. Raijmakers, Jan Coen Netelenbos, Joop P. van den Bergh, Elisabeth M. W. Eekhoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
fibrodysplasia ossificans progressiva
heterotopic ossification
high-resolution peripheral quantitative computed tomography
bone strength
bone microarchitecture
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.627784/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.627784/full

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