Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells

Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells

Abstract Background Toll-like receptor 4 (TLR4) plays an important role in the elimination of Gram-negative bacteria infections and the initiation of antiinflammatory response. Using the technology of pronuclear microinjection, genetically modified (GM) sheep with TLR4 overexpression were generated....

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Bibliographic Details
Main Authors: Xiaofei Guo, Jinlong Zhang, Yao Li, Jing Yang, Yihai Li, Chunxiao Dong, Guoshi Liu, Zhengxing Lian, Xiaosheng Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Biological Research - Thessaloniki
Subjects:
TLR4-overexpressing
Peripheral blood mononuclear cells
Transcriptome
Sheep
Online Access:http://link.springer.com/article/10.1186/s40709-020-00124-3

Internet

http://link.springer.com/article/10.1186/s40709-020-00124-3

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