Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs

Abstract Background Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with the dysregulation of MMPs is unknown....

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Bibliographic Details
Main Authors: Kun Du, Min Wang, Nan Zhang, Pei Yu, Ping Wang, Ying Li, Xiangdong Wang, Luo Zhang, Claus Bachert
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Clinical and Translational Allergy
Subjects:
Online Access:https://doi.org/10.1002/clt2.12059