The Deubiquitylating Enzyme USP4 Cooperates with CtIP in DNA Double-Strand Break End Resection

The Deubiquitylating Enzyme USP4 Cooperates with CtIP in DNA Double-Strand Break End Resection

DNA end resection is a highly regulated and critical step in DNA double-stranded break (DSB) repair. In higher eukaryotes, DSB resection is initiated by the collaborative action of CtIP and the MRE11-RAD50-NBS1 (MRN) complex. Here, we find that the deubiquitylating enzyme USP4 directly participates...

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Bibliographic Details
Main Authors: Hailong Liu, Haoxing Zhang, Xiaohui Wang, Qingsong Tian, Zhaohua Hu, Changmin Peng, Pei Jiang, TingTing Wang, Wei Guo, Yali Chen, Xinzhi Li, Pumin Zhang, Huadong Pei
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009535

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http://www.sciencedirect.com/science/article/pii/S2211124715009535

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