Neurotoxic Activity of the HIV-1 Envelope Glycoprotein: Activation of Protein Kinase C in Rat Astrocytes

Abstract: Envelope glycoprotein (gp120) of the human immunodeficiency virus type one (HIV-1), has adverse effects on glial cells and neurons. This study reports on the direct effect of recombinant gp120 (r-gp120) produced from different expression systems on protein kinase C, as a measure of relativ...

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Bibliographic Details
Main Authors: Isaac Adebayo, Eric Hunter, Etty N. Benveniste, Scott Parker, Rong Wu, Oyewole Adeyemo
Format: Article
Language:English
Published: MDPI AG 2002-11-01
Series:International Journal of Molecular Sciences
Subjects:
HIV
Online Access:http://www.mdpi.com/1422-0067/3/11/1105/