Berberine promotes glucose consumption independently of AMP-activated protein kinase activation.

Berberine is a plant alkaloid with anti-diabetic action. Activation of AMP-activated protein kinase (AMPK) pathway has been proposed as mechanism for berberine's action. This study aimed to examine whether AMPK activation was necessary for berberine's glucose-lowering effect. We found that...

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Bibliographic Details
Main Authors: Miao Xu, Yuanyuan Xiao, Jun Yin, Wolin Hou, Xueying Yu, Li Shen, Fang Liu, Li Wei, Weiping Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4114874?pdf=render