Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients

Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients

Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important model animal for infectious diseases, behavioral science and metabolic science, for which more experimental tools are becoming available. Here, we desc...

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Bibliographic Details
Main Authors: Rong Li, Baoling Ying, Yanan Liu, Jacqueline F. Spencer, Jinxin Miao, Ann E. Tollefson, James D. Brien, Yaohe Wang, William S. M. Wold, Zhongde Wang, Karoly Toth
Format: Article
Language:English
Published: The Company of Biologists 2020-08-01
Series:Disease Models & Mechanisms
Subjects:
crispr
syrian hamster
adenovirus
animal model
knockout
Online Access:http://dmm.biologists.org/content/13/8/dmm044602

Internet

http://dmm.biologists.org/content/13/8/dmm044602

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