Increased B cell and cytotoxic NK cell proportions and increased T cell responsiveness in blood of natalizumab-treated multiple sclerosis patients.

BACKGROUND: Changes in the blood lymphocyte composition probably both mediate and reflect the effects of natalizumab treatment in multiple sclerosis, with implications for treatment benefits and risks. METHODS: A broad panel of markers for lymphocyte populations, including states of activation and c...

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Bibliographic Details
Main Authors: Johan Mellergård, Måns Edström, Maria C Jenmalm, Charlotte Dahle, Magnus Vrethem, Jan Ernerudh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3847051?pdf=render