Crystallographic study of PET radiotracers in clinical evaluation for early diagnosis of Alzheimers

Crystallographic study of PET radiotracers in clinical evaluation for early diagnosis of Alzheimers

The title compound, C24H25NO3·2CH3OH, which crystallized as a methanol disolvate, has applications as a PET radiotracer in the early diagnosis of Alzheimer's disease. The dihedral angle between the biphenyl rings is 8.2 (2)° and the heterocyclic ring adopts a half-chair conformation with the N...

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Bibliographic Details
Main Authors: Angela Altomare, Elena Capparelli, Antonio Carrieri, Nicola A. Colabufo, Anna Moliterni, Rosanna Rizzi, Dritan Siliqi
Format: Article
Language:English
Published: International Union of Crystallography 2014-11-01
Series:Acta Crystallographica Section E
Subjects:
crystal structure
ligands
P-glycoprotein inhibitor
PET radiotracer
hydrogen bonds
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536814021400

Internet

http://scripts.iucr.org/cgi-bin/paper?S1600536814021400

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