Single Cell RNA-Seq Analysis Identifies Differentially Expressed Genes of Treg Cell in Early Treatment-Naive Rheumatoid Arthritis By Arsenic Trioxide

Single Cell RNA-Seq Analysis Identifies Differentially Expressed Genes of Treg Cell in Early Treatment-Naive Rheumatoid Arthritis By Arsenic Trioxide

Objective: Early treatment-naïve rheumatoid arthritis (RA) has defective regulatory T (Treg) cells and increased inflammation response. In this study, we aim to illustrate the regulation of Treg cells in pathogenesis of early rheumatoid arthritis by arsenic trioxide (As2O3).Methods: We studied the e...

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Bibliographic Details
Main Authors: Chunling Li, Tianshu Chu, Zhiyi Zhang, Yue Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
arsenic trioxide
regulatory T cell
T helper 17 cell
single cell RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.656124/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.656124/full

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