Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

As assembling 60S subunits transit from the nucleolus to the nucleoplasm, they undergo significant changes in protein composition and structure. Here, the authors provide a structural view of interconnected events during the middle steps of assembly that include the maturation of the central protube...

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Bibliographic Details
Main Authors: Jelena Micic, Yu Li, Shan Wu, Daniel Wilson, Beril Tutuncuoglu, Ning Gao, John L. Woolford
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17534-5