The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin

The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin

Oleanolic and ursolic acids are natural triterpenic compounds with pentacyclic cholesterol-like structures which gives them very low water solubility, a significant disadvantage in terms of bioavailability. We previously reported the synthesis of inclusion complexes between these acids and cyclodext...

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Bibliographic Details
Main Authors: Codruţa Soica, Camelia Oprean, Florin Borcan, Corina Danciu, Cristina Trandafirescu, Dorina Coricovac, Zorin Crăiniceanu, Cristina Adriana Dehelean, Melania Munteanu
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
oleanolic acid
ursolic acid
cyclodextrin
DMBA
TPA
mouse model
synergism
Online Access:http://www.mdpi.com/1420-3049/19/4/4924

Internet

http://www.mdpi.com/1420-3049/19/4/4924

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