Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung

<p>Abstract</p> <p>Background</p> <p>The patient population receiving long-term oxygen therapy has increased with the rising morbidity of COPD. Although high-dose oxygen induces pulmonary edema and interstitial fibrosis, potential lung injury caused by long-term exposur...

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Bibliographic Details
Main Authors: Ishizaka Akitoshi, Shibata Tetsuichi, Kawashiro Takeo, Yamasawa Fumihiro, Aoki Takuya, Urano Tetsuya, Okada Yasumasa
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/9/1/37