Three GLI2 mutations combined potentially underlie non‐syndromic cleft lip with or without cleft palate in a Chinese pedigree

Three GLI2 mutations combined potentially underlie non‐syndromic cleft lip with or without cleft palate in a Chinese pedigree

Abstract Background Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect. Its etiology is complex and it has a lifelong influence on affected individuals. Despite many studies, the pathogenic gene alleles are not completely clear. Here, we recruit...

Full description

Bibliographic Details
Main Authors: Peiqi Meng, Huaxiang Zhao, Wenbin Huang, Yunfan Zhang, Wenjie Zhong, Mengqi Zhang, Peizeng Jia, Zhibo Zhou, Gulibaha Maimaitili, Feng Chen, Jieni Zhang, Jiuxiang Lin
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
cleft lip and/or palate
GLI2
hereditary pedigree
pathogenic mutation
whole‐exome sequencing
Online Access:https://doi.org/10.1002/mgg3.714

Internet

https://doi.org/10.1002/mgg3.714

Similar Items