HCV Protease Inhibitory, Cytotoxic and Apoptosis-Inducing Effects of Oleanolic Acid Derivatives

Purpose: To evaluate oleanolic acid derivatives on liver disease related bioactivities, 29 oleanolic acid derivatives of several series were tested for their inhibitory activity on hepatitis C viral protease and for their cytotoxic effects on Hep G2 cells. Results: The amino derivatives showed poten...

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Bibliographic Details
Main Authors: Chao-Mei Ma, Xiu-Hong Wu, Masao Hattori, Xi-Jun Wang, Yoshihiro Kano
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2009-09-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/5631