Exploring the feasibility of using real-world data from a large clinical data research network to simulate clinical trials of Alzheimer’s disease

Abstract In this study, we explored the feasibility of using real-world data (RWD) from a large clinical research network to simulate real-world clinical trials of Alzheimer’s disease (AD). The target trial (i.e., NCT00478205) is a Phase III double-blind, parallel-group trial that compared the 23 mg...

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Bibliographic Details
Main Authors: Zhaoyi Chen, Hansi Zhang, Yi Guo, Thomas J. George, Mattia Prosperi, William R. Hogan, Zhe He, Elizabeth A. Shenkman, Fei Wang, Jiang Bian
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-021-00452-1