Identification of Genes Essential for Antibiotic-Induced Up-Regulation of Plasmid-Transfer-Genes in Cephalosporin Resistant Escherichia coli

Identification of Genes Essential for Antibiotic-Induced Up-Regulation of Plasmid-Transfer-Genes in Cephalosporin Resistant Escherichia coli

Bacterial conjugation is one of the most important mechanisms for spread of antibiotic resistance among bacteria. We have previously demonstrated that cefotaxime (CTX) exposure up-regulates expression of Type-IV conjugation transfer genes, and that this leads to increased transfer of a blaCTX–M–1 en...

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Bibliographic Details
Main Authors: Gang Liu, John Elmerdahl Olsen, Line Elnif Thomsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
antibiotic induced conjugation
cefotaxime
blaCTX–M–1 resistance plasmid
transfer genes
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02203/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02203/full

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