Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model.

Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model.

Cord blood (CB) is increasingly used as a source of hematopoietic stem cells (HSC) for transplantation. Low incidence and severity of graft-versus-host disease (GvHD) and a robust graft-versus-leukemia (GvL) effect are observed following CB transplantation (CBT). However, its main disadvantages are...

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Bibliographic Details
Main Authors: Michelle Escobedo-Cousin, Nicola Jackson, Raquel Laza-Briviesca, Linda Ariza-McNaughton, Martha Luevano, Sophie Derniame, Sergio Querol, Michael Blundell, Adrian Thrasher, Bernat Soria, Nichola Cooper, Dominique Bonnet, Alejandro Madrigal, Aurore Saudemont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605799?pdf=render

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http://europepmc.org/articles/PMC4605799?pdf=render

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