Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

Abstract Outbreaks of Yellow Fever occur regularly in endemic areas of Africa and South America frequently leading to mass vaccination campaigns straining the availability of the attenuated Yellow Fever vaccine, YF-17D. The WHO has recently decided to discontinue regular booster-vaccinations since a...

Full description

Bibliographic Details
Main Authors: Michael Kongsgaard, Maria R. Bassi, Michael Rasmussen, Karsten Skjødt, Søren Thybo, Mette Gabriel, Morten Bagge Hansen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Soren Buus, Anette Stryhn
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00798-1