Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons

Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons

Diabetes predisposes to cognitive decline leading to dementia and is associated with decreased brain NAD<sup>+</sup> levels. This has triggered an intense interest in boosting nicotinamide adenine dinucleotide (NAD<sup>+</sup>) levels to prevent dementia. We tested if the adm...

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Bibliographic Details
Main Authors: Krish Chandrasekaran, Joungil Choi, Muhammed Ikbal Arvas, Mohammad Salimian, Sujal Singh, Su Xu, Rao P Gullapalli, Tibor Kristian, James William Russell
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
NAD<sup>+</sup>
NMN
diabetes
dementia
cognitive impairment
mitochondria
Online Access:https://www.mdpi.com/1422-0067/21/11/3756

Internet

https://www.mdpi.com/1422-0067/21/11/3756

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