IgG and IgA with Potential Microbial-Binding Activity Are Expressed by Normal Human Skin Epidermal Cells

IgG and IgA with Potential Microbial-Binding Activity Are Expressed by Normal Human Skin Epidermal Cells

The innate immune system of the skin is thought to depend largely on a multi-layered mechanical barrier supplemented by epidermis-derived antimicrobial peptides. To date, there are no reports of antimicrobial antibody secretion by the epidermis. In this study, we report the expression of functional...

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Bibliographic Details
Main Authors: Dongyang Jiang, Jing Ge, Qinyuan Liao, Junfan Ma, Yang Liu, Jing Huang, Chong Wang, Weiyan Xu, Jie Zheng, Wenwei Shao, Gregory Lee, Xiaoyan Qiu
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
immunoglobulin G
immunoglobulin A
human epidermis
VDJ rearrangement
microbial-binding
Online Access:http://www.mdpi.com/1422-0067/16/2/2574

Internet

http://www.mdpi.com/1422-0067/16/2/2574

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