Genetic Screening for Potential New Targets in Chronic Myeloid Leukemia Based on Drosophila Transgenic for Human BCR-ABL1

Genetic Screening for Potential New Targets in Chronic Myeloid Leukemia Based on Drosophila Transgenic for Human BCR-ABL1

Chronic myeloid leukemia is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome that originates from the reciprocal translocation t(9;22)(q34;q11.2) and encodes for the constitutively active tyrosine kinase protein BCR-ABL1 from the <i>Breakpoint Cluster...

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Bibliographic Details
Main Authors: Marco Lo Iacono, Elisabetta Signorino, Jessica Petiti, Monica Pradotto, Chiara Calabrese, Cristina Panuzzo, Francesca Caciolli, Barbara Pergolizzi, Marco De Gobbi, Giovanna Rege-Cambrin, Carmen Fava, Claudia Giachino, Enrico Bracco, Giuseppe Saglio, Francesco Frassoni, Daniela Cilloni
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
chronic myeloid leukemia
BCR-ABL1
Rab family
Drosophila melanogaster
genetic screening
Online Access:https://www.mdpi.com/2072-6694/13/2/293

Internet

https://www.mdpi.com/2072-6694/13/2/293

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