Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum

Summary: Projections from the nucleus accumbens to the ventral pallidum (VP) regulate relapse in animal models of addiction. The VP contains GABAergic (VPGABA) and glutamatergic (VPGlu) neurons, and a subpopulation of GABAergic neurons co-express enkephalin (VPPenk). Rabies tracing reveals that VPGl...

Full description

Bibliographic Details
Main Authors: Jasper A. Heinsbroek, Ana-Clara Bobadilla, Eric Dereschewitz, Ahlem Assali, Reda M. Chalhoub, Christopher W. Cowan, Peter W. Kalivas
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300322