Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

The hemispheric, bi-layered optic cup forms from an oval optic vesicle during early vertebrate eye development through major morphological transformations. The overall basal surface, facing the developing lens, is increasing, while, at the same time, the space basally occupied by individual cells is...

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Bibliographic Details
Main Authors: Stephan Heermann, Lucas Schütz, Steffen Lemke, Kerstin Krieglstein, Joachim Wittbrodt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05216