FtsZ Interactions and Biomolecular Condensates as Potential Targets for New Antibiotics

FtsZ Interactions and Biomolecular Condensates as Potential Targets for New Antibiotics

FtsZ is an essential and central protein for cell division in most bacteria. Because of its ability to organize into dynamic polymers at the cell membrane and recruit other protein partners to form a “divisome”, FtsZ is a leading target in the quest for new antibacterial compounds. Strategies to pot...

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Bibliographic Details
Main Authors: Silvia Zorrilla, Begoña Monterroso, Miguel-Ángel Robles-Ramos, William Margolin, Germán Rivas
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antibiotics
Subjects:
bacterial cell division
FtsZ association states
protein interactions
biomolecular condensates
macromolecular crowding
phase separation
Online Access:https://www.mdpi.com/2079-6382/10/3/254

Internet

https://www.mdpi.com/2079-6382/10/3/254

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