Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect.

Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic triglyceride accumulation, ranging from steatosis to steatohepatitis and cirrhosis. NAFLD is a risk factor for cardiovascular diseases and is associated with metabolic syndrome. Antihyperlipidemic drugs are recommended as part of...

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Bibliographic Details
Main Authors: Fang Yan, Qi Wang, Chao Xu, Mingfeng Cao, Xiaoming Zhou, Tingting Wang, Chunxiao Yu, Fei Jing, Wenbin Chen, Ling Gao, Jiajun Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057124?pdf=render